Tymlos Titration Scedule?
I’m newly diagnosed with severe osteoporosis. My doctor and insurance have settled on Tymlos as the treatment. I’ve had some past drug sensitivities, even drug allergies, so I’m intrigued by the fact that others have posted here about titrating on Tymlos. My doctor has said there is NO titration for Tymlos and that the pen can only deliver the 80mcg dosage. Can those of you that have titrated share the titration schedule you have used and how the pen is adjusted to deliver smaller dosages?
Thank you.
Interested in more discussions like this? Go to the Osteoporosis & Bone Health Support Group.
Connect

Interesting to hear everyone’s experiences! I am 67 with osteoporosis, having tried Evenity followed by Reclast.
Did nothing for past 2 + years except weight training and walking. Held my own, even improved to just over line to osteoporosis now.
Started Tymlos about a week ago at 2 clicks, then 3 and this morning did 4 ( half normal dose)
Doing okay but feeling a little dizzy and tired. Will stay at 40 mcg for a week or so. And continue to exercise.
How are you all doing with your dosage schedules?
@leslie2121 Started 2, 4, 6, then 8. Bad headaches at 8. Went back to 2 for a couple weeks. Then 4 every other day for two weeks. Now 6 each evening. No headaches but noticeably “off” for several hours each day. Also notice mild muscle/joint pain flare ups randomly during the day. Manageable. Will likely be told to go to full dose soon.
-
Like -
Helpful -
Hug
1 ReactionI’m still at 4 clicks and feeling “off” too- tired, a little nauseated- hoping it clears. Will stay at 4 until better.
I think you could stay at 6 or try 7 as your max dose?
I will be reporting in to my endocrinologist next week as to my tolerance at 6 clicks. I won't be surprised if he encourages me to go to 8. I'm a little surprised you are taking your during the day. I was told it is best to take it at night so if there is nausea or dizziness you "sleep it off"!
@jbcat26 I thought I would take it at night too, but it seems to keep me awake if I do.