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Replies to "Actually, a study about this was done well more than a year ago. They found that..."
Prostate Cancer | Last Active: 11 hours ago | Replies (12)
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Actually, a study about this was done well more than a year ago. They found that even if you had an undetectable PSA, you could still have metastasis grow.
Here’s a link to an article from 2007 about it.
https://pubmed.ncbi.nlm.nih.gov/17171704/
Here’s another article from 2022
https://pmc.ncbi.nlm.nih.gov/articles/PMC12984609/
Replies to "Actually, a study about this was done well more than a year ago. They found that..."
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@jeffmarc Yes, disease progression does occur with no PSA but most of those identified had very advanced prostate cancer prior to the no PSA progression with 95% metastatic (69% castrate resistant), 67% with prior chemo. The 93% on ADT w/77% ARSI might also have something to do with the undetectable PSA. It appears that this should not be very concerning to the typical patient that had RP or RT as a first treatment. It is very unlikely that if they have a first recurrence it will not be detected by PSA.