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diastolic dysfunction effects and treatmetn
Heart & Blood Health | Last Active: 5 hours ago | Replies (19)Comment receiving replies
Hi @asolidrock
Yes, Jardiance has been shown to help patients with heart failure.
Here is what I found online that you may find interesting:
Jardiance (empagliflozin) is an SGLT2 inhibitor FDA-approved to reduce the risk of cardiovascular death and hospitalization for heart failure in adults, regardless of diabetes status or left ventricular ejection fraction (LVEF). It is the first therapy to demonstrate significant benefit for both heart failure with reduced ejection fraction (HFrEF) and heart failure with preserved ejection fraction (HFpEF), addressing a previously significant unmet medical need.
The medication works by promoting the excretion of excess sodium and glucose through urine, which reduces fluid retention and lowers the workload on the heart. Clinical trials (EMPEROR-Reduced and EMPEROR-Preserved) showed that Jardiance significantly decreases the combined risk of cardiovascular death and heart failure hospitalization, with benefits observed in patients with or without type 2 diabetes.
Common side effects include increased urination, genital yeast infections, and urinary tract infections (UTIs). Jardiance is typically taken as a 10 mg tablet once daily and may cause modest weight loss or lower blood pressure. Serious but rare risks include ketoacidosis (even in non-diabetics) and dehydration, particularly if used with other diuretics.
This is the beauty of Mayo Clinic Connect...we can learn so much from each other!
Have you thought to ask your cardiologist if this would be something that may help you?
Replies to "Hi @asolidrock Yes, Jardiance has been shown to help patients with heart failure. Here is what..."
@karukgirl Thanks. I have grade 1 left ventricular dysfunction. Hadn’t heard of this treatment. In fact I’m not being treated at all for it. Came from having Covid a year ago, which supposedly is not uncommon.
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@karukgirl
Thanks for your feedback. I I believe my LVEF is mild at this point and am on Jardiance - or HFrEF is probably the proper terminology and I understand the way Jardiance works. I am having lung function testing in a week. I'll be eager to see what that shows. My frustration is that I can still work hard and/or go for a brisk walk but am totally drained afterwards. (I know - I'll be 78 in 2 weeks), but I was a runner, x-c skier, biker....and am frustrated w/my body shutting down to the point where I feel like I can hardly move after exercise.
I do appreciate Mayo Clinic Connect for the opportunity to learn from others and if my lung function tests show nothing significant, I will contact my cardiologist again and ask where to go next....