@gajokos Support is great, and declining treatment that doesn't work for you is fine by me. I do, however, think that people sometimes blame unrelated ills on HU, that rationale for alternative treatments should be sourced with something more than "I read somewhere that ..." and that outright misinfo needs to be corrected.

Did you do anything for erythromelalgia? I had this before taking HU, but it still comes back occasionally. Oncology said, yup, that happens, just gotta deal with it. Cool water or compresses about the only thing I've found that works.

Not a motorbike aficionado, but I did some freelance work for Harley-Davidson many years ago. Absolutely nicest, most collaborative clients I ever had. Seemed like a great company. A local Harley Owners Group here does fund-raisers for vets and sick kids. I enjoy chatting with them about their bikes--and then beat it when they crank up the music.