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Evenity and Bone Markers

Posted by marymj7 @marymj7, Sep 10, 2024

Can testing bone markers part way through Evenity treatment indicate whether or not it's working? My baseline numbers are what I believe Dr. McCormack would label as optimal, yet I have severe osteoporosis. CTX in the 200s. P1NP 39. I will have bone markers tested soon ahead of my fourth set of Evenity injections. Has anyone had bone markers done while on Evenity?

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slrausch | @slrausch | Jun 30 11:29am
In reply to @cathyf31 "@followheart87 The rule of thumb some docs follow, based on research & number-crunching) is to.maintain a..." + (show)
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@followheart87 The rule of thumb some docs follow, based on research & number-crunching) is to.maintain a P1NP : CTX ratio greater than or equal to 150 (meaning you are anabolic...aka in a building bome state). (Recent talk has dropped that to >= 130. Your ratio is 219 = 100 ÷(457/1000). Great!!

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@cath

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slrausch | @slrausch | Jun 30 11:29am

What is the lab you had drawn?

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rjd | @rjd | Jul 1 3:48pm
In reply to @cathyf31 "@followheart87 The rule of thumb some docs follow, based on research & number-crunching) is to.maintain a..." + (show)
Profile picture for CathyF31 @cathyf31

@followheart87 The rule of thumb some docs follow, based on research & number-crunching) is to.maintain a P1NP : CTX ratio greater than or equal to 150 (meaning you are anabolic...aka in a building bome state). (Recent talk has dropped that to >= 130. Your ratio is 219 = 100 ÷(457/1000). Great!!

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@cathyf31 Could you please advise the source of your information about calculating the ratio and what the result means? Thanx

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CathyF31 | @cathyf31 | Jul 1 4:39pm
In reply to @rjd "@cathyf31 Could you please advise the source of your information about calculating the ratio and what..." + (show)
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@cathyf31 Could you please advise the source of your information about calculating the ratio and what the result means? Thanx

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@rjd

I first came across the P1NP : CTX ratio idea on this site via someone else's post. See below for the veey interestung video.

VIDEO of P1NP : CTX/1,000 (Anabolic > 150)
https://connect.mayoclinic.org/comment/1558097/

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CathyF31 | @cathyf31 | Jul 1 4:43pm
In reply to @rjd "@cathyf31 Could you please advise the source of your information about calculating the ratio and what..." + (show)
Profile picture for rjd @rjd

@cathyf31 Could you please advise the source of your information about calculating the ratio and what the result means? Thanx

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@rjd Also, I can't recall where I heard they are now thinking the anabolic threshhold is closer to 130 (rather than 150). It may have been on the video from the Washington DC 2026 symposium that provided a summary of some key updates and guideline changes, etc. It was a recent post, either earlier this week or maybe last week. Pretty sure that's where I heard the 130 for the first time.

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followheart87 | @followheart87 | 19 hours ago

My doctor was happy with my 6-month CTX and P1NP results and said the rise in CTX is due to bone remodeling. She wants me to get a follow up Dexa scan after the 12th injection.

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