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Nubeqa Monotherapy vs Dual Therapy with ADT
Prostate Cancer | Last Active: Jun 30 2:37pm | Replies (18)Comment receiving replies
@jeffmarc wrote " The nice thing about [Darolutamide] is that it has no side effects for most people. Apalutamide on the other hand does have side effects and can cause brain fog."
I think you mean specifically cognitive side-effects. Darolutamide has many general side-effects (as is the case for all ARSIs):
https://www.mayoclinic.org/drugs-supplements/darolutamide-oral-route/description/drg-20470011
The instance of cognitive side-effects seems to be in the low single digits for Apalutamide, percentage-wise, but if you're one of the unlucky ones, switching to Darolutamide is an option.
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@northoftheborder
While there may be listed side effects for Darolutamide, I have heard from a couple of dozen people at least, that are on it, and have found no side effects at all. I have heard from a couple of people that had side effects, but it was after stopping and starting again. There were a couple of cases where people reduce the dosages of it, But the side effects they reported were from ADT, more likely, since they were on both.
If you were to attend an Ancan.Org Advance prostate cancer meeting you would hear them constantly telling people to switch to Darolutamide. Listen to one of the previous sessions and you can hear it. That’s because it works so well.
I didn’t bring it up, but fatigue is a commonly reported problem with Apalutamide, Not really a problem for most people with Darolutamide.