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Nubeqa Monotherapy vs Dual Therapy with ADT

Prostate Cancer | Last Active: Jun 30 2:37pm | Replies (18)
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Profile picture for ucla2025 @ucla2025

I assume he means dropping the Orgovyx and going monotherapy with just Nubequa while watching PSA. I am making this assumption having read about the EMBARK and LIBERTAS studies. I believe those studies suggest that patients who drop to PSA <.2 after six months on ADT + ARPI could go to only the ARPI to improve their quality of life, with close tracking of PSA of course. Am I missing something?

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Replies to "I assume he means dropping the Orgovyx and going monotherapy with just Nubequa while watching PSA...."
Jeff Marchi | @jeffmarc | Jun 29 7:18pm

@ucla2025
Intermittent usually means stopping and starting. You definitely don’t get much benefit doing that with ADT.

I would ask the doctor what they specifically were thinking about.

Nubeqa alone works quite well and can probably keep the PSA undetectable for a long time. It would be nice if the doctor would let him do that.

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