Evenity vs Forteo/Tymlos for first Osteo drug?

Posted by heleneruth @heleneruth, Nov 23, 2025

Hi everyone,
I am 61 and received my 1st dexi last June despite yers of me asking for one. My dexi was horrible, shocked my doctors. I have severe osteoporosis. I had a feeling it would be bad, but not this bad. ( I have had 2 periods of rapid significant weight loss in the last 10 years, serious ongoing stress, limited ability to exercise due to chronic back injury, and family histroy of osteo yet they wouldn't give me a DEXI till now!) I can pull up the numbers but honestly it makes me so anxious that I try to avoid looking at the report. I am deciding between Evenity or Forteo/Tymlos. The doctor wants me on an anabolic first.Evenity would actually be cheaper for me as it's covered under Medicare Part B while Forteo co-pay is $900/month for me! I am medicare due to disability with my back. I am terrified of having these meds cause more back pain. Also I have chronic muscle and general fatigue and these meds seem to have potential side effects on muscle/bone aches. Also I'm concerned with the Evenity and the potential unintended immune response, since my chronic muscle fatigue is likely of autoimmunity cause (immune mediated reaction to a virus, 40 years ago). The physiatrist doctor in my smallish town doesn't seem to know much-she says they have the same efficacy and rarely have side effects. Well that is not what I've read! I'm scared and confused. Thanks for any guidance.

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Profile picture for njx58 @njx58

@marcelalondero Not an effect of Evenity, no.

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@njx58 porque está en un efecto rara vez de da. Justo estuve preguntando por otro lado. Pero si me lo dices, me quedo más tranquila, ya que mi reumatologa tarde en responderme. Gracias

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Profile picture for marcelalondero @marcelalondero

@judycat Quisiera saber si a alguien le dió disfonía o laringitis con Evenity. Por favor comenten. Me quedé sin voz de repente

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@marcelalondero
a rare side effect of Evenity can be angioedema Either an allergic reaction or, because Evenity is a monoclonal antibody, an antibody reaction. It can impair the ability to breath and swallow. Your loss of voice could be an indication of swelling in the vocal cords. Any voice changes should be reported to the prescribing physician.

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@marcelalondero
a rare side effect of Evenity can be angioedema Either an allergic reaction or, because Evenity is a monoclonal antibody, an antibody reaction. It can impair the ability to breath and swallow. Your loss of voice could be an indication of swelling in the vocal cords. Any voice changes should be reported to the prescribing physician.

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@gently el dolor intercostal es otro tema no sé si es efecto de Evenity. Gracias por tu respuesta

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Marcela,
Para resolver tu duda de forma rápida, el dolor o los espasmos musculares son efectos secundarios conocidos de Evenity (romosozumab), que a menudo se manifiestan en la zona de las costillas y la espalda. Sin embargo, el dolor en el pecho también requiere atención médica inmediata para descartar afecciones cardiovasculares graves.
Espero que todo salga bien.

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