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Intraductal Prostate Cancer: Any info about recurrence rates?

Posted by biker70 @biker70, Nov 4, 2024

Anyone on here have intraductal prostate cancer and low Gleason? I was diagnosed this year and had surgery. Gleason 3+4 and clear pathology except intraductal. Doctors just say follow up PSAs which have been thankfully, undetectable. However I am not understanding future reoccurrence rate and which medications/treatments I will need. Anyone on this forum with intraductal?

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Jeff Marchi | @jeffmarc | Jun 23 11:01am
In reply to @florida11 "I was diagnosed at age 51 with intraductal PC. I was Gleason 4+3=7 with a tertiary..." + (show)
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I was diagnosed at age 51 with intraductal PC. I was Gleason 4+3=7 with a tertiary score of 5. My PSA was only about 2.0 at the time.That was late 2017.

I had surgery in December 2017, then a recurrence after about 10 months. Then I had radiation to the prostate bed and two years of ADT. Once I got off it, and testosterone started to rise, my PSA did as well. Next, I had radiation to the abdomen region due to a reoccurrence in a lymph node. I did 18 months of ADT. Once my testosterone started to rise, it showed up on my hip bone. After that, my oncologist recommended that we hit it hard with six rounds of chemotherapy and going on Lupron and Nubeqa indefinitely. My last chemo infusion was October 2025.

I hope this helps. I wish you the very best of luck. Happy to talk more if helpful.

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@florida11
Intraductal is extremely hard to treat. Sorry to hear you have it repeatedly coming back.

Have you had hereditary, genetic testing? The fact that you got it so young and that your father has it could be due to a genetic problem. You also might benefit from getting a somatic, genetic test as well to see if any of your metastasis have given you a genetic anomaly.

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