Has anyone found a treatment that helps with peripheral neuropathy?

Posted by bigjohnscho @bigjohnscho, Jul 1, 2025

I suspect that everyone on this forum has been searching for a medication that helps their neuropathy and even though you no that all the internet claims are false we continue to waste hundreds of pounds. Desperation is a powerful force. Has any one been fortunate enough to find a genuine treatment. I just can’t believe that there are so many awful people who prey on our vulnerability and knowingly orchestrate such elaborate scams.

Interested in more discussions like this? Go to the Neuropathy Support Group.

I was diagnosed with Peripheral Neuropathy and Rheumatoid Arthritis in 2015 when I was 55 years old. I was declared 100 % disabled at the same time by Social Security and had to retire.
Think I have been to every kind of Doctor and have had every kind of procedure to correct my Balance,Walking, my Pain and sleepless nights! Nothing worked for all of the problems I had?
After I had used up all my physical therapy from Medicare I decided that I would have to do this on my own! I got a membership to my gym and I started going into training to make my body relearn everything I had lost! So I started going to the gym 3 days a week at 5 A.M. and doing the things I learned in physical therapy. I treated it like my JOB. I was also seeing a Pain Management Doctor during this whole thing and they monitored my progress and adjusted my medications the whole time. After seeing all these different miracle cures that claim everything and do nothing? I found out the only thing that really works is exercise and Pain Medication!!
After over 10 years of this I am as close to being normal as I will ever be. I am 66 years old now and I play golf 3 days a week (Walking) and go to my gym 2 days a week at 5 A.M. and I take Gabapentin,Methocarbamol and Hydrocodone every day under my doctors care.
This will be what I have to continue to do for the rest of my life or until they find a cure for these
diseases? These are the hard facts that do work. It can be verified by my Doctors. I hope this helps someone?

REPLY

Please talk with your provider before starting any type of treatment or supplements….. the treatments mentioned may work for many people but your provider knows your medical history and should be the one advising you.

REPLY

I seldom read the new so called cures for my peripheral foot neuropathy. I’ve wasted hundreds of pounds without any success. Has anyone discovered anything that shows some promise. Do you think they ever will. Good luck everyone,keep searching and hoping
John.

REPLY

I have had on in my feet for many years. I also have pulsing in my legs and twitching from my ankles when I lie down. My feet feel like they’re in bindings as well. All of this happens only when I’m lying down.
I have been to numerous doctors and had one procedure to free a pinched nerve. Nothing has helped. I take 3 tablets of magnesium during the day and 300 mgs. of Gabapentin before bed. They seem to help me sleep and most nights I do sleep well despite the neuropathy.

REPLY
Profile picture for rkh950 @rkh950

I have been using Alpha Lipoic Acid 600 mg and Wes tab one which is a B vitamin and use Mama Bear Oasis cream on my feet when needed for the past several months and I have seen much improvement. From what I read, Neuropathy does not go away, but one can live with it taking supplements that help it be more bearable.

Jump to this post

@rkh950 I tried and loved capsaicin but now I’m taking vitamin B 12 500 mcg which help a lot! My doctor gave me a Rx of NSAID-arthritis pain reliever. I quit the capsaicin because the vitamin B 12 500 helped so much more.

REPLY
Profile picture for John, Volunteer Mentor @johnbishop

I take Na-R-ALA and Methylcobalamin B12 together in the morning and evening daily along with other neuropathy supplements described in another post here - https://connect.mayoclinic.org/comment/957496/.

Jump to this post

@johnbishop
what brand of Na-R-AlA do you use?

REPLY

Neuropathy is nerve pain caused by their missing insulation. Vitamin C grows new nerves but only vitamin B12 insulates them. Just like electric wires. Take PLENTY of B12 . Best form is METHYLCOBALAMIN. Best food sources are liver and mussels. The very foods most people never eat.

REPLY
Profile picture for granny73 @granny73

@rkh950 I tried and loved capsaicin but now I’m taking vitamin B 12 500 mcg which help a lot! My doctor gave me a Rx of NSAID-arthritis pain reliever. I quit the capsaicin because the vitamin B 12 500 helped so much more.

Jump to this post

@granny73 At last. Someone has found out about vitamin B12.

REPLY

I have taken 300 mg of Lyrica since 2014. I had severe burning, stinging starting from feet and radiating up my legs. I could not even sleep. The drug has help me tremendously.

REPLY
Profile picture for jamessaxo @jamessaxo

Neuropathy is nerve pain caused by their missing insulation. Vitamin C grows new nerves but only vitamin B12 insulates them. Just like electric wires. Take PLENTY of B12 . Best form is METHYLCOBALAMIN. Best food sources are liver and mussels. The very foods most people never eat.

Jump to this post

Interesting. I've been told I have small fibre neuropathy. I've been through all the hoops, consulted neurologists and others.
I did read, on Facebook of all places, an article about vitamin b12 deficiency. In the UK a blood test is done checking possible culprits for your symptoms. Mine was, mainly, an ice cold sole of left foot but both affected; sometimes burning, always tingling.Maddening. Relief when in bed at night. This article said that the standard NHS test for b12 is flawed, as it measures total b12. There is active and non active b12. Only active should be measured. To cut a long story short I challenged my GP, no joy. So, eventually I oaid for a private test on active b12. It was 30% below the lowest on normal range. My GP checked this then put me on 6 loading doses of b12 over 2 weeks. I've had to continue pushing but,with neurological issues, the Nice ( NHS overseeing body), guidelines state that the injections should then continue every other day until no further improvement. That's where I am. It's early days but I'm hopeful.
I've been tested for pernicious anaemia but it was negative. However it seems that test doesn't pick up all cases so I'm thinking about next stepson this. PA is main cause of b12 deficiency. Not the only one though. Proton Pump Inhibitors taken long term are a cause too( that's used for acid reflux). And others.
I'll update in a few weeks..

REPLY
Please sign in or register to post a reply.