It is hard to get a blood cancer diagnosis. Give yourself time and space to grieve the person you were before. It is hard to get used to your “new normal”. People can have the same diagnosis, but experience different symptoms and different reactions to the treatments which can be confusing and frustrating. Don’t be afraid to try the treatments and advocate for other ones when you need to. Fatigue is a very common effect of MPNs the treatments do not always alleviate fatigue either. So sometimes you have to adopt lifestyle changes that help you cope with it. I wish you the best in your journey and I hope you find a treatment and lifestyle and diet changes that work for you. (I feel pretty good now and I have reduced my platelets from about 700,000 to 450,000. I started treatment with 500 mg daily HU because I was symptomatic, not because I was high risk. On HU for about 1.5 years).