@gravity3

There is a good article on the topic: https://mcpress.mayoclinic.org/women-health/testosterone-not-just-for-men/

My cardiologist advised me to stay away from testosterone because I have known coronary artery disease (CAC score 38). Her concern was that the long-term cardiovascular safety of testosterone in women remains uncertain, so she felt it was prudent to avoid additional exposure given my underlying risk factors. That said, I’m quite happy with my current regimen of transdermal estradiol and micronized progesterone. I’ve experienced minimal side effects, better sleep, and satisfactory suppression of bone turnover markers, which was my primary goal.