@drbart86 Well, two things: first, we have different mutations, to start with. Secondly, you're drinking way too much cranberry juice. I drink 8 oz. per day, diluted 50/50 with water to reduce the natural sugar content. Actually, that's half an 8oz glass, topped off with water, so really I'm drinking 4 oz of juice. This has been enough to keep my bloodpressure normal and, based on my reading, I expect it will keep my platelet count normal, too. That's all I want. I will still have my mutation and my ET, of course. If anyone thought I was saying otherwise, they simply misread me.