@drbart86 I never said anything about cranberry juice being a solution to any genetic mutation. But then, neither is Hydroxyurea. The best either can do is keep platelet count stable and that is all I am hoping for from the cranberry juice. My CALR Exon 9 mutation will be with me until I die. That's not my concern here. Keeping my platelet count normal with food instead of drugs that have side effects is. If I can do this with cranberry juice, then I have no further need for the Hydroxyurea. It isn't going to cure me of my mutation, either, but if I continue taking it, it is for certain that I will never have a normal red cell count. Since (according to my hematologist) it's the Hydroxyurea that is lowering my red cell count, then not using the Hydroxyurea is the way to normalize my red cell count. That is my goal, not curing my mutation, and, as I said, Hydroxyurea cannot cure my mutation, either.

@drbart86 Well, two things: first, we have different mutations, to start with. Secondly, you're drinking way too much cranberry juice. I drink 8 oz. per day, diluted 50/50 with water to reduce the natural sugar content. Actually, that's half an 8oz glass, topped off with water, so really I'm drinking 4 oz of juice. This has been enough to keep my bloodpressure normal and, based on my reading, I expect it will keep my platelet count normal, too. That's all I want. I will still have my mutation and my ET, of course. If anyone thought I was saying otherwise, they simply misread me.