Stopping anastrozole

Posted by gma1942 @gma1942, Jun 3 1:54pm

I have only taken anastrozole for 6 months but want to stop taking it. Do you have to taper off or can you just stop?

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Profile picture for lifetraveler @lifetraveler

Hi! @vegada :

Kudos to you and your friends for the perseverance and patience of taking Anastrozole for more than 6.2 years and counting! Most importantly you guys have been keeping these BC cells away from your bodies since your diagnosis, congratulations!

Thanks for sharing your inspiring experience!

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@lifetraveler Thank you so much for your kindness. I really appreciate it. I hope you have a great week.

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Profile picture for sequoia @sequoia

@forrestbeach26 I took Anastrozole for 2 yrs and like you it turned me Old. Thank goodness no vomiting. Just joints. I quit it. It took me about 3-4 months to get back to normal. My reoccurrence % was low. Quality of life is the key.
Good luck & blessings on your journey

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@sequoia
I have been on Anastrozole for about 2 yrs (half dose) My metastatic B/C to a vertabrae has been all the while in "sleep" mode I am told, thank god! But I have had dental sugery issues that have prvented me from having more than 2 Zomeda infusions and another D surgery in the next mo or so. The onc. said finish all that surgery, BUT my scans did come back w/ osteopenia in some lower torso to /hip area to now osteoperosis there.
I feel ok, but am anxious and not comfortable with this PA's telling me they will now prescribe me Tamoxafin . I know it has failed a lot of B/C patients pre menopausal and has a side effect of causing a secondary gynocolgical cancer (CELL MUTATION) (the % vary of how many patients present with a new cancer) I have a family history of hysterectomies and do not assess that taking this pill expressly for the presence of osteoperosis is ideal for my particular journey that I have been on off & on largely due to bad surgeons in Fl that did not address a some cancer cells she stated she "left behind" & then oncologists ignoring a lump in my arm pit that I was insisting is very questionable & passing it off as "probably just scar tissue", then begging for a biopsy 4 yrs later as it was growing & a new surgeon who said, "I am NOT going to be too "aggressive with the margins around this tumor" . 2 yrs later I happened to feel something hard there...thankfully I moved in the Pand. to NC w/ Duke B/C Ctr by sheer chance in '21. The Anastrozole is in part causing the Osteoperosis. I read here that Anastrozole acumulates to a certain degree in one's system. True? Also how does Tamoxifen process? does it acumulate or not? Postmenopausal experiences w/ B/C & Tamoxifen anyone?
I just feel it's amazing w/ my keeping up my healthy diet etc, that somehow the B/C is in one Vertabrae has not progressed at all and I am taking a better Calcium absorbing pill now (CAL D3, Mag K2 & doing more strength exercises & trying to up my calcium through more calcium rich foods is worth trying and then getting my 3rd Zomeda infusion in 2.5 yrs would be worth trying before a daily Tamaxofin med. Thoughts, experiences?

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You do not have to taper, it will slowly leave your system. I took it for 3 mos and did pretty well, just felt old and had anxiety. Then I had vestibular neuritis and was told not to take it for a few days. I then decided to stop taking it, I’m too afraid that it contributed to the severe vertigo attack which debilitated me for a couple of weeks and from which I still have some residual effects. My chance of recurrence is 5-6% without an AI and 2-3% with it.
I had a 8mm DCIS, HR/PR+HER2-, with a small less than 4mm foci of IDC with a Ki67 score of 2. I had a lumpectomy and radiation. I am 71 and taking or not taking anastrozole doesn’t change my life expectancy, only reduces my recurrence rate. I have mild osteopenia and I don’t want to worsen it either. It’s truly a personal decision that you need to look at everything to help you.
If I were younger or had a larger chance of recurrence, I would certainly “bite the bullet” and take it. Hugs and best wishes.

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