When asked the same question, a board certified rheumatologist at Vanderbilt Medical Center said that Mounjaro/Zepbound has anti-inflammatory qualities and is perfectly acceptable for use by PMR patients. I was on prednisone for over a year, finally managed to taper off with the help of Kevzara and have been on Mounjaro for 6 weeks with a weight loss of 15 pounds. Remarkable. The only side effects have been predictable but tolerable GI conditions, that are lessening as time goes on.