Breast enlargement in men due to hormone therapy.
Has anyone experienced breast enlargement due to hormone therapy used to treat stage 4 prostate cancer. I recently discontinued the use of Zytiga (Abiraterone) due to shortness of breath, and breast enlargement. My breathing was completely restored within 48 hours of discontinuing Zytiga, however the breast enlargement has not abated after one month. Has anyone heard of any treatments that would restore the breasts to normal size. Thank you. Philnob.
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I am suffering the opposite--reduction in size of the penis. What can be done for that?
@texasnole I am taking 5 mg Cialis daily to improve blood flow and using a vacuum device after showers to stretch the tissue. I have experienced some shrinkage that I hope will resolve normally after completing ADT. http://www.pcri.org hosted an online seminar last week with a sexual health specialist who had several suggestions. His session is about an hour, worth watching.
I'm not sure about returning to normal, but I believe some short radiation treatments to the nipples can stop the process. Worth a discussion with your oncologist.
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2 Reactions@miked77 I Am almost 2 yrs post prostate surgery radiation and 2 rounds of Lupron, not only are my breasts large but for past year my nipples hurt when touched or rub against something. Talked to oncologist said it should go away but not yet , anyone have this issue and for this long ?
I just started the Estradiol patch and salvage radiation a few days ago and I will start Zytiga any day; both drugs are for 2 years. I think the patch increases the likelihood of breast enlargement, compared to other ADT.
Has anyone looked into radiating the breasts prophylactically? My RO says if I were to do it, I should do it soon (i.e., next week). He says risk of cancer from the additional radiation is 1/1000, and that there isn't a ton of data on how well it works. If you have done this (or done it later in the process), please share your experience. Thanks.
@lsk1000
Well, I too have recently experienced big weight gain (10 lbs in 3 days) and body change. Can’t keep getting new shorts and pants that fit! 36 waist to 33 trim during stress phase and now snug in 34 regular waist due to new layers of waist blubber. Aargh. I exercise nearly every day. Don’t see any ideas for change until drugs (Orgovyx and Nubequa) end. Will keep charging forward.
Mark 4+3 Olio-1
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1 Reaction@bikeman1
Hey, I found this old post by @aldenrobert and thought this might give you some extra info : ). You can find many more if you use "search" option : )))
"I want to thank everyone that commented on my original post. Sorry for the long post here.
After reading everything here I contacted my Medical Oncologist and Radiation Oncologist to see what thought. Both of them are maybe in their early 30s. My Medical Oncologist said that the newer drugs has less of a chance of those side effects than older drugs. I said that the new drugs I was on Erleada and Orgovyx were what caused my gynecomastia. He replied that it wouldn't do any harm to talk to the Radiation Oncologist. The R.O. said the same thing as my M.O. , I said that it already happened and that I would be going back on ADT in the future. He agreed that treatment for it would be appropriate but that he did not do that procedure himself. But he was able to refer me to a Radiation Oncologist closer to home ( I live 2 1/2 hours away from my P.C. medical team).
The new R.O. was a man in his early seventies. At our first meeting I knew that he had read my whole Prostate cancer chart. He said "You have been through a lot in the past three years". He could name every one of the Doctors that had treated me and what treatments they did. Before he even examined me I also knew that he had actually looked a my most recent scans. He said that my left breast was larger than my right. And said it was likely because I already had radiation the the right breast area when I had the radiation treatments for a tumor in my right Hiluim (a lymph node attached to my right lung).
He told me about what the treatment entailed. It was just three short sessions of radiation to my breasts. He told me about some minor side effects. Asked if it was something I wanted to proceed with. I said yes but that my M.O. and other R.O. were less than enthusiastic about it though. He replied that was because they were young. He explained that back in the day when actual physical castration was standard treatment for advanced Prostate cancer this would have also been standard treatment. He said my others Oncologists are too young to have practiced when those treatments were standard.
I finished my last of the three radiation treatments Friday. Only side effect was a little redness.
I think that I will be back on some sort of ADT by the end of the month. I will have lab work done and see my Medical Oncologist Monday."
Have been experiencing some minor breast and abdomen increases after 18 months of Orgovyx and Zytiga. Hoping that things might return to normal once I complete my 24 month treatment? I believe there are medications that will stop additional gynocomastia but do not reverse it and may come with other side effects. Radiation to the breast area can be done prior to treatment, but I understand it's not as effective as the medications.
@oumike “resolve on its own”? I have the frustrating problem with breasts and belly. I doubt it will be resolved as long as I am on hormone therapy. In my case on Nubeqa monotherapy 44 months. My research finds that the blocked/unused T is enzymatic converted to estrogen, which causes the problem.
Thanks all, and especially to Mrs. Surf for gently and diplomatically reminding me that there is a "search" function here. 🙂
I went back to the Estradiol Initiative--the source that convinced me to try the patch in the first place--where there is some data on this issue. While enlargement occurs in a lot of men on the patch, it seems like most is pretty small. I am going to pass on the radiation; I just don't feel like doing something else to my body.
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