The Role of Repurposed Drugs in Prostate Cancer Therapy

@daveys In a comment up above I did list one of them. There are many, from many different sources, but the ones I am most familiar with, and have been learning about, are the ones listed in the book "Fight Cancer Like a Man" by Dr. Stephen Peterutti. I'm sensitive to copyright infringement, so I am not comfortable continuing to list them, as I did previously list them as part of a conversation started by another member in this group. However, because I want people to have the information and do their own research, I will list them here, but this will be the last time I will specifically list the repurposed drugs included in the above-referenced book. If people want his specific recommendations/protocols and rationale for those, I highly recommend getting the book and spending time reviewing the information. The paperback version is currently $19.99 on Amazon, and the Kindle version is $8.99.

The list of repurposed drugs Dr. Petteruti includes in his book are Sirolimus (Rapamune), Metformin, Low-Dose Naltrexone (LDN), Doxycycline, Atorvastatin, Ivermectin, Menbendazole, Mistletoe (Viscum), and Itraconazole. I discussed Atorvastatin in quite a bit of detail in an above comment if you would like to reference it.

I can understand people's interest in having "a list". But, as I stated in my original post/question... I am interested in what others have learned about repurposed drugs for prostate cancer. This needs to be a "conversation" to provide the most benefit. I understand input will run the gamut from "there is no such thing as repurposed drugs helping fight prostate cancer" to "this or that repurposed drug cured my friend's prostate cancer". I get that, and I welcome it all... the spectrum of experiences and opinions. We each have our own individual process of taking in information, determining what makes sense to us, deciding whether or not to pursue researching it, acting upon it, etc.

I have to tell you, reading Dr. Petteruti's rationale for considering the above-noted repurposed drugs, has definitely spurred me to do additional research. His approach is that repurposed drugs can serve a purpose "in the arsenal" of fighting prostate cancer, he, in no way, conveys that they are the sole method. We need to make our bodies "inhospitable" to cancer, period. And if a repurposed drug can serve that purpose, we need to at least be aware of that possibility, research it for ourselves, and, at the end of the day, come to our own conclusions, and act accordingly.

I do think we need to have a conversation about "care professionals", which came up in an earlier response to my post. Who do we trust as authorities in our health journey, and why? I will provide my thoughts on this when I have the opportunity to come back to this forum. Thank you.

@daveys Hello. I just wrote a reply, but, fyi, it is "under review". Thank you.

@heavyphil
I would call those as "supportive" or "complementary" - drugs that can possibly make cancer cells more effected by ACTUAL cancer drugs and "in theory" of course, never proven to do so but nobody did randomized trials either, I guess.

Estrogen is proven to control PC the same way as regular ADT does , so Estrogen is truly repurposed drug.

PC's "indolence" (even in the most aggressive form) is both blessing and a problem.

Blessing because patients can live for many years, but it is a problem since PC is not easily and readily recognized by our immune system and that is why immunotherapy development goes so slow. That is why patients have to be on ADT for so long since PC cells are so slow to divide and to die off after radiation.

@surftohealth88 An MD firmer patient of mine was under AS; had G3+3 like 4 times in a row…docs wanted to cut.
He went on a regimen of metformin, doxycycline, Vit D and a statin.
A year later, no G3+3…not even PIN! Lost contact with him since retirement.
I’ve read about this regimen since then; and if it works at all it’s probably only effective in very early low grade cases…but it worked for him.
Phil

@heavyphil

Good for him 👍 !

Maybe he had spontaneous remission - that happens too : ))).

We will never know what helps without clinical randomized trails : (((. Perhaps it will happen somewhere in Europe again (like it did for Estogen patch) , where health care is not so money driven : (((.

Ran across this today and found it very interesting.
https://pmc.ncbi.nlm.nih.gov/articles/PMC11595001/