This is a very promising new first line trial. Glad you are on it. Who is your doctor here in AZ? I've been on a clinical trail here @ Mayo in AZ (Pemigratinib-a gene inhibitor drug that targets the FGFR2 mutation) and on it I've have stable disease with a high quality of life for 18 months now. See my post earlier this morning about all the available resources at the Cholangiocarcinoma Foundation. Happy to connect with you locally---I've been through the gem/cis regimen(back in 4/18) and come out the other side so happy to offer you some hopeful words if you need them. ---Andrea