Thank you Kanaaz - to be clear, the metastasis is not IN the brain, but ON a bone. Some spreading into the brain can be seen on the MRI, but they are not calling it brain cancer. I've read the article you referenced above. Very technical but I did understand some of it. Prognosis does not sound too good, but then again that can be said for cholangiocarcinoma in general. My oncologist suggested we are probably seeing this rare metastasis because I am living longer than initially expected. At my diagnosis almost 3 years ago, they said I had maybe 2 years, so I'm beating the odds! Thanks again for the information. If you find anything else, please share. ~Kris