Here is my story:
PCa Dx in May 2023:
MRI in April 23 detected malignity tumor of size 1.2 cm, PI-RADS 4. MRI showed no sign of cancer on pelvis area and neighboring lymph nodes.
Biopsy 2. may 23. Results:
PSA day before biopsy: 6.2
3 out of 10 confirmed cancer in peripheral zone right side GS: 2 x 3+3 and 1 x 3+4 (GP4 - 40%) . Clinical stage: T2a.
RALP in 6. June 23:
Histology results:
tumor location & size: Right dorsal lateral / 14 x 8 mm
tumor type: Acinar adenocarcinoma
presence of Intraductal carcinoma: positive
number of tumors: 1
Gleason score 4+3 (70% pattern 4 with cribriform morphology)
EPE: negative, SV: negative, microscopic bladder neck and lympho-vascular infiltration: negative, surgical margins: negative, pT2
GS is upgraded to 4+3. In addition the pattern 4 is now found to be of type Intraductal cribriform.
3 months post RALP performed adjuvant lymph node dissection, due to upgrade of cancer. 9 nodes are removed and examined. no cancer detected.
PSA <0.1 (6 weeks post RALP)
PSA <0.1 (1 year post RALP, June 2024)
PSA ultrasensitive < 0.006 (18. September 2024)
PSA <0.01 (12. Dec.2024)
PSA <0.01 (1, April 2025)
PSA 0.008 Ultrasensitive (21. May 2025)
PSA <0.01 (10. Aug. 2025)
9. Sep 2025 : PSA <0.01 ng/mL - AFP <1.82 ng/mL - CA19-9 =10.4 U/mL - CEA = 1.6 ng/mL - S100 melanoma cancer marker 0.19ng/ml (S-100 shall be under <0.15 ng/ml)
PSA <0.01 (13, November 2025)
PSA <0.01 (16, December 2025) - S100 melanoma cancer marker 0.14ng/ml (16, December 2025)
PSA 0.01 (20, January 2026)
PSA < 0,1 (19. February 2026)
PSA 0.01 (25, April 2026)
Unfortunately the less sign is gone in last two tests and cribriform is Large, see picture. I am afraid that the cancer is coming back. I insisted for adjuvant rad. and ADT after RALP, but MO wanted to wait and watch PSA. (However I got 9 lymph node dissection that showed no cancer).