Hi @donnademps As you will see if you look back through my posts, I'm also in Canada (Alberta). When I started Camzyos there was a REMS program (can't remember exactly what REMS stood for) which paid 100% of the cost for me, which at the time was supposedly over US$80,000 per year! Even if it's down to "only" CA$22,000, that's still inaccessibly high for most of us. I thought I heard that REMS had been stopped but I also thought I heard that there were other means to work around that financial hurdle. Most health insurance that I have heard of (in Canada anyway), probably including provincial plans, have a catastrophic drug cost clause in which you pay up to a certain amount and then the plan takes care of everything over that. All that to say, keep talking to your cardiologist about it - he will be in-the-know about how to handle it.

Regarding side effects and other people's experiences, this has been a miracle drug for some of us and has been a miserable disappointment for others. I'm one of the lucky ones. The big, black-box warning that says "may cause heart failure"? First, realize that "heart failure is not "heart attack." Heart failure is a syndrome where the heart struggles to pump or relax properly - which sounds a lot like HCM to me. And HCM itself can cause heart failure. So for me, I could live with a condition that could cause heart failure, or I could take a medication that could cause heart failure, but could also help make my debilitating symptoms go away. But even I did a whole lot of hand-wringing before I came to that conclusion, and not everyone will feel that way. As I have said several times before, listen to your doctor(s) & cardiologist, not to some idiot who posts things on the internet (i.e. "me"). My experience may be of value to you, but my advice is not. It sounds like your cardiologist is really dialled in! Feel free to send me a private message if you want to discuss in more detail. Best of luck with Camzyos or with whatever other treatment you get!