@mangos I am on a variety of medication’s and/or supplements. So I’m not sure what you’re after by asking the question. However, none of it caused the insulin resistance. Insulin resistance is genetic/hereditary. I did a great job for 40 years, but my age went out. It’s actually kinda nice to be on the insulin resistance medicine metformin because now I can eat a little bit of sugar. Things changed dramatically after menopause and a little bit of sugar is good to avoid dehydration, along with a touch of salt. Neither I could eat for 40 years. Now it’s kind of mandatory. I have a little bit because I stay active and it’s easy to dehydrate when you lose your muscle mass. When I was young, I did not believe in supplements, but I took care of my dad and over the years. I got to understand that age plays apart of your body no longer being able to digest properly. The things you put into it. So now I play in the supplements and there are specific ones which were very helpful. Vitamin D was amazing at bringing down the A1c for the last 15 years. Periodically, I had to increase it. I might be due for an increase again. I take vitamin code for women over 50 and for me HEME iron is a major player because I have always had anemia of one form or another. B12’s are critical to as they aid in iron absorption and other supplements being absorbed properly. Our bodies are well oiled machines, and when the oil can runs dry, we have to refill it and sometimes change the formula!