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It depends on the diagnosis, and stage of the cancer, to begin with. Other considerations which weren't paid to me was that carboplatin/paclitaxel combo therapy wasn't going to work as my cancer was platinum resistant, as cancer was not resolved, and came back worse within a couple of months.
I was switched to Enhertu (administered in a clinical study--which is ongoing), after other tests including biopsies of tissues were taken.
I've been on this trial for 1 year and 5 months, with infusions every 3 weeks. It's tough and there is no end date, but it worked! I have high grade 3C1 serous cell endometrial cancer HR2+.
So to recap tell us type and stage your cancer is, and I'm sure other participants here can give you answers.
Good luck and try not stress out.

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Replies to "It depends on the diagnosis, and stage of the cancer, to begin with. Other considerations which..."

@cookercooker I too have same cancer. Having 1st treatment of doxorubicin on the 25th. It will be my 4th type of chemo. The Herceptin nor the Enhertu worked for me. I say it didn't because my CA125 always went up. I only had 4 treatments of Enhertu and read that it can take that or more to see results with it. Lab work was done before the 4th treatment of it and I'll have labs the 19th but not a CA125. I'm stage 3C, diagnosed 2/2025. Had hysterectomy in Aug 20th, 2025. Couldn't remove any lymph nodes because they were tangled in vascular system. My numbers however did go from 1641 to 80 on the carboplatin and paclitaxal in 4 months. Since surgery they have continued to climb. Puzzling.

@cookercooker I've been following you since you first began posting here. I'm so glad to know that your current treatment of Enhertu is working for you.

You are so right that cancers are not all alike. The oncologist and cancer care team considers the type and stage of cancer in order to recommend the treatment that will be tailored to you.

Here is my go-to website for the description of types and stages of endometrial cancers. This website has helped me to formulate my questions for my cancer care team.

American Cancer Society: What is Endometrial Cancer?

-- https://www.cancer.org/cancer/types/endometrial-cancer/about/what-is-endometrial-cancer.html

Mayo Clinic: Endometrial Cancer:

-- https://www.mayoclinic.org/diseases-conditions/endometrial-cancer/symptoms-causes/syc-20352461