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Optimal Duration of Hormone Therapy

Prostate Cancer | Last Active: 6 hours ago | Replies (60)

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@jim18
I have completed just about 18 months of ADT plus ARPI. I could be wrong, but I didn't get the feeling that it was a cost issue to get the darolutamide. In fact, she mentioned that their institution has a very good track record at getting insurance approvals. Being my Dexa scan was good and PSA is undetectable I'll likely not pursue shortening the regimen at this point. The side effects I'm dealing with are annoying but have been tolerable. In fact, this may sound silly, but as much as I am looking forward to getting off ADT, I'm worried as to what will happen when that happens.

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Replies to "@jim18 I have completed just about 18 months of ADT plus ARPI. I could be wrong,..."

@swl1956 Then it might just be you do not seem to have many issues with the Zytiga. The ADT/ARSI suppress the PSA so you cannot tell how effective your treatment has been until a few months after you go off of them. I think everyone is apprehensive at that point. It is not unusual for the PSA to be detectable (more with 4-6 vs. 24 months ADT). Then need to wait another few months to make sure the PSA is still moving down.