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Anyone have a positive Cologuard test?

Colorectal Cancer | Last Active: Jun 20 1:48am | Replies (306)

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Profile picture for silaswright @silaswright

Good morning, I am not a fan of colorguard tests. I had a positive test come up in December 2025 and with the size of the pre-cancerous growth, the Gastro DRs suspected it had been growing for 8 to 10 years. With that timeline, I had 2 maybe 3 false-negative colorguard. I wish I had known and done the colonoscopy screening instead. My primary care didn’t seem to know the data on the colorguard and I regret not researching myself.

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Replies to "Good morning, I am not a fan of colorguard tests. I had a positive test come..."

@silaswright My husband had a positive test in November and end of January, they found a large tumor in his cecum. It was quite large. He had had about 15 or 20 FIT (like Cologuard) tests throughout the years and the doctors said if you have no family history, you are not at high risk, so go ahead with the FIT. And I guess according to what they tell people (the 10 year thing), he had at least 10 false negatives and now he has a real mess with metastatic colon cancer. I have read research just recently that the false positives are worse than we think and some of the tumors (like sessile (flat) tumors) and ones on the right side (the ascending colon) are more likely to be false negative because they don't tend to bleed and if they don't bleed, those fecal tests are not reliable.

Anyway, hoping the best for you. If it's precancerous, there's a whole lot they can do to treat you.