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First Session of Radiation Called Off While on Radiation Table
Prostate Cancer | Last Active: Jun 6 6:36pm | Replies (16)Comment receiving replies
Be glad that they stopped and noticed there were major differences. It probably shouldn’t take too long to get him back on the table.
If he has the PTEN genetic Problem there is a new treatment.
Capitello produces FDA results
This year and last, Astra Zeneca spent a lot of money at GU ASCO advertising its PTEN mutation solution, capivasertib (Truqap). It's a drug the FDA has already approved to target PTEN mutations in breast cancer.
Yesterday the FDA's ODAC (Oncology Drugs Advisory committee) voted to advance capi for prostate cancer in conjunction with abiraterone + prednisone, based on the Capitello trial. This is initially for men with metastatic disease carrying a PTEN mutation. PTEN is one of the 3 Bad Boy Tumor Suppressor Growth mutations, along with TP53 and RB1.
Here's what its maker, Astra Zeneca had to say. Two AnCan Advisory Board GU med oncs strongly favor capi, Drs. Efastathiou and George. In fact Dr. George gave evidence at the ODAC hearing.
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@jeffmarc
Thanks, Jeff, for the new PTEN treatment info. This is another line of attack if needed. Right now, my husband is only two months into ADT and his aggressive cancer is still considered contained in the prostate, although we know how sneaky it can be.
Yesterday, the Duke medical oncologist said no other scans are done to check on the cancer unless the PSA level begins to rise. (This was when I asked how they monitor the cancer over the next two years on ADT.) Is this standard - no scans unless PSA levels rise? Just an assumption that all is well based on PSA?