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Husband prostate cancer metastasized to liver non small cell

Posted by ckelberman @ckelberman, Jun 3 5:48am

Hi all. Like all, it’s been tough. Husband currently has liver metastasis non small cell and will start carboplatin and cabazitaxel chemo tomorrow. Non psma uptake. Also has some bone lesions and lymph nodes. Went through 10 rounds Docetaxal last one 12/3/25. Would love to read folks experience with this and also be directed to all chats relevant. After the 10th round hospitalized and treated for pjp and neutropenia. Doing all maintenance doses of meds to minimize effects this time. Appreciate all input and direction. We are in N Virginia and he is being treated at Schar Cancer Center. Many thanks,

Interested in more discussions like this? Go to the Prostate Cancer Support Group.

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surftohealth88 | @surftohealth88 | Jun 3 5:15pm

I am really sorry to hear that 😔.

Unfortunately I do not know much about liver metastasis but just wanted to try and "bump" this question up so other members with more experience might see it.

Sending you hugs and wishing your husband a complete healing from PC mets in very near future. 🍀

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Mrs K | @klein505 | Jun 3 6:00pm

I am so sorry to hear that. I know some hospitals break up liver mets with ultrasound, but I don't know how effective it is, or if it is suitable in your husband's condition.
https://southfloridahospitalnews.com/cleveland-clinic-uses-noninvasive-ultrasound-technology-to-treat-some-liver-tumors/

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ckelberman | @ckelberman | Jun 3 6:15pm
In reply to @surftohealth88 "I am really sorry to hear that 😔. Unfortunately I do not know much about liver..." + (show)
Profile picture for surftohealth88 @surftohealth88

I am really sorry to hear that 😔.

Unfortunately I do not know much about liver metastasis but just wanted to try and "bump" this question up so other members with more experience might see it.

Sending you hugs and wishing your husband a complete healing from PC mets in very near future. 🍀

Jump to this post

@surftohealth88 Thank you for your kind words. Appreciate you bumping this back up.

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ckelberman | @ckelberman | Jun 4 5:38am

Wanted to bring this back to the top of the support forum. Thanks to all the support. 1st chemo cocktail scheduled today for my husband. We will forge ahead. A very wise oncology vet yes vet once said to me and I will share and always keep the advice with me, “stay the course”. And we will stay the course till it changes……

In the limited time of my reading the support group chats, I have learned a lot. All of you are compassionate and wonderful people. God bless. I too will chip in and share any side effects that my husband experiences……this may be helpful to someone searching for information

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dpayton | @dpayton | Jun 4 9:51am

I, too, don't know anything about this particular metastasis but I just wanted to wish you and hubby the best possible outcome! Don't give up. Sending hugs....

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beaquilter | @beaquilter | Jun 5 8:46am

Aww doesn't sound good at all, My husband did docetaxel last summer and hair came back by Christmas time. He did really well overall, was tired most days- the tiredness kicks in day 3 I think it was (the day before and the day after he was the energizer bunny from the Prednisone) then he'd feel like crap for a good week, then fine for a week and then back for another round! (He got a strange side effect from the Prednisone- hiccups!! for like 45 min and nothing helped until a friend said to breathe into a paper bag until you can't stand it anymore! it helped but he had to do it each time or when he woke up at night, the hiccups would start again)
It's not in his liver but was stage 4 everywhere else in his body it seemed! (bones, spine, lungs, pelvis, lymph nodes and of course prostate) Now it's a lot less- still in those spots but not as big and most medium spots have disappeared, but there's a handful of stubborn spots still left.
He eats pretty perfectly and exercises every day and tried to stay active around the house.
How's your husband feeling?
Has he been offered Pluvicto or other drugs? Radiation?
What's his PSA now and what was it to start?
hugs

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ckelberman | @ckelberman | Jun 6 4:50am

Thank you everyone for your support. Liver lesions not a candidate for Pluvicto. He was scheduled for it. The lesions did not display any PSMA uptake. Thank you.

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Moderator
Colleen Young, Connect Director | @colleenyoung | Jun 16 7:54pm
In reply to @ckelberman "Thank you everyone for your support. Liver lesions not a candidate for Pluvicto. He was scheduled..." + (show)
Profile picture for ckelberman @ckelberman

Thank you everyone for your support. Liver lesions not a candidate for Pluvicto. He was scheduled for it. The lesions did not display any PSMA uptake. Thank you.

Jump to this post

@ckelberman, I'm tagging a few additional members like @perrychristopher @amee @edmond1971 @ringmastr1 and @proftom2, who have experience with prostate cancer metastasizing to the liver.

You may also wish to use the group search to find related and relevant discussions: https://connect.mayoclinic.org/group/prostate-cancer/

Were they able to increase your husband's white blood cells with the neutropenia treatment? How are YOU doing?

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1 reply
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ckelberman | @ckelberman | 6 days ago
In reply to @colleenyoung "@ckelberman, I'm tagging a few additional members like @perrychristopher @amee @edmond1971 @ringmastr1 and @proftom2, who have..." + (show)
Profile picture for Colleen Young, Connect Director @colleenyoung

@ckelberman, I'm tagging a few additional members like @perrychristopher @amee @edmond1971 @ringmastr1 and @proftom2, who have experience with prostate cancer metastasizing to the liver.

You may also wish to use the group search to find related and relevant discussions: https://connect.mayoclinic.org/group/prostate-cancer/

Were they able to increase your husband's white blood cells with the neutropenia treatment? How are YOU doing?

Jump to this post

@colleenyoung thank you for helping direct this. Would totally appreciate any information from the folks you tagged on this

We are hanging in. It’s a new regimen with different side effects and we are managing through them. The Neulesta shot after chemo was helpful. I still have panic attacks on off thinking about all that’s going on. I am sure I am not alone.

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Profile picture for ckelberman
ckelberman | @ckelberman | 6 days ago
In reply to @beaquilter "Aww doesn't sound good at all, My husband did docetaxel last summer and hair came back..." + (show)
Profile picture for beaquilter @beaquilter

Aww doesn't sound good at all, My husband did docetaxel last summer and hair came back by Christmas time. He did really well overall, was tired most days- the tiredness kicks in day 3 I think it was (the day before and the day after he was the energizer bunny from the Prednisone) then he'd feel like crap for a good week, then fine for a week and then back for another round! (He got a strange side effect from the Prednisone- hiccups!! for like 45 min and nothing helped until a friend said to breathe into a paper bag until you can't stand it anymore! it helped but he had to do it each time or when he woke up at night, the hiccups would start again)
It's not in his liver but was stage 4 everywhere else in his body it seemed! (bones, spine, lungs, pelvis, lymph nodes and of course prostate) Now it's a lot less- still in those spots but not as big and most medium spots have disappeared, but there's a handful of stubborn spots still left.
He eats pretty perfectly and exercises every day and tried to stay active around the house.
How's your husband feeling?
Has he been offered Pluvicto or other drugs? Radiation?
What's his PSA now and what was it to start?
hugs

Jump to this post

@beaquilter thank you for the information. Sorry for the tardy response. I was helping triage hubbys symptoms and side effects from cycle 1 earlier. Now on day 17. Trying to get him to regain most of the weight loss prior to start of cycle 2 next week.

Hope both of you are hanging in. May I ask if there are any follow ups w Pluvicto or other treatments following docetexal? My husband completed docetexal early December 2025. They are going to do focal radiation on 2 lesions on the spine from this past weeks MRI while he is on chemo…

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