@dmcj well before I got on the medication I was having severe symptoms as well. TIA’s horrible migraines, difficulty breathing. I didn’t have a diagnosis yet until they did bloodwork so once the blood counts came down with the medication thing started to level out I’m sure getting an opinion from Mayo Clinic will help figure out what’s right for her. You’re doing the right thing. I hope she finds relief. I’m a nurse and I did work through the whole process at the hospital, but I ended up quitting after five years and I’m now doing something less strenuous.