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@jspr422

Bisphosphonates have the fewest problems and are usually the first line of treatment. I am on Atelvia. Not every MD likes or recommends it, but my specialist did (Rheumatologist, I also have Discoid Lupus that is well-managed). You take it right after breakfast. Atelvia doesn't build bone, but slows the loss. My specialist retired but she would have likely kept me on it until I fractured something or my bone scores dropped below a certain point. Twelve years on it, so far (with drug holidays). I just found another Rheumatologist I trust; we'll see what he recommends. I exercise just like you do (likely more walking and less lifting though). Besides a DEXA, you can also get a TBS (Trabecular Bond Score).

I have found that endos and PCPs want to prevent bone loss and put you on Prolia "right away" and "forever," which I consider an off-label use. I am unsettled by the fact that much or all of the bone Prolia builds can evaporate if you don't keep to the six months injection schedule or quit cold turkey (w/o going to another drug to mitigate but not eliminate the loss). What happens if I get sick or become senile and forget about the shots? I also call Prolia bone, "fake bone,". likely an unfair moniker for what some view as a miracle drug. I think PCPs, knowing how painful lumbar spine fractures/frailty can be, want to be proactive and prevent it. The research and recommendations however, are a little more conservative on when to switch from a bisphosphonate, but maybe the research/recommendations are behind the times with so much clinical experience in existence now. I found my new Rheumatologist on Castle and Connolly. If you Google the requirements for getting listed and how the company turns a profit, I think you will find their listed MDs as great a resource as I do.

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Replies to "@jspr422 Bisphosphonates have the fewest problems and are usually the first line of treatment. I am..."

@researchmaven

The current thinking seems to be anabolics first then bisphosphonates. The positive effects of the anabolic can muted with the old sequencing treatment plan but we are all are different with different needs.