← Return to AML, age 78, taking Decetabine/ Venetoclax, no transplant

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Profile picture for Lori, Volunteer Mentor @loribmt

Hi @sonieaml The article I sent you was mostly just informative. The combo treatment is for new AML patients who can’t tolerate intensive chemo. It is in regards to the combination of drugs along with the INQOVI.
I mostly sent it to you so you could see the efficacy of the drug. INQOVI has really made a huge difference for some AML patients.

Your current story is nothing short of miraculous. To have those two mutations which are now undetectable is amazing. Years ago, if intensive chemo wasn’t an option, there wasn’t much hope for AML patients with FLT3 and NPM1. I had those two mutations, plus another. I was able to have the intensive chemo but even then I was in the high category for relapse. The chemo would only be good for another round or so and then I was out of options without the transplant. So, just in 7 year’s time there have been so many major changes for us older patients.
With your two mutations in complete remission there would be no reason to continue with the V & D. That is really outstanding! I wish you well with this transition to the INQOVI for the SF3B1 mutation.
As always, you know I want to follow along with you. We become family here… hugs!

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Replies to "Hi @sonieaml The article I sent you was mostly just informative. The combo treatment is for..."

@loribmt
Thank you so much!
I know how blessed I am and continue to be on this AML/MDS journey. The timing of my diagnosis and treatment has been better than I have ever expected. When I declined the BMT my records showed 12 months and palliative care! My friend who was with me when I got my diagnosis and watched as I received my intensive induction therapy thought I would never come home from the hospital - she still cries and calls me a miracle too when we talk about how my care team and treatment(s) have given me my life back!
Blessings to you and EVERYONE on the Mayo connect site!