You might want to consider Kevzara but it doesn't decrease your pain as quickly as Prednisone does. A biologic might be your best option simply because of preexisting osteoporosis and glaucoma. Kevzara is well suited for people with PMR who can't tolerate Prednisone or for people with conditions that are exacerbated by Prednisone.

You need to give Kevzara up to 3 months for the "full effect" but it will lower your ESR quickly. You will most likely still have pain when you start Kevzara. Prednisone is usually still given as a "bridge" to rapidly relieve your pain until Kevzara has time to reach its full effect. With any luck, you should be able to reduce your Prednisone dose quickly when Kevzara is started along with Prednisone. You could just "tough it out" and take Kevzara alone but most people like the immediate pain relief that Prednisone provides.

Kevzara is costly. Some insurance companies "require" Prednisone to be tried first for PMR and then maybe a DMARD like methotrexate. In your case, you may need to submit an authorization request for Kevzara and the reasons why Prednisone is contraindicated. Preexisting osteoporosis and glaucoma are very good reasons for not wanting to take Prednisone.