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Pluvicto - How long do side effects last?

Prostate Cancer | Last Active: 1 day ago | Replies (12)

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@johnravens
Not sure if you’ve heard that Pluvicto works really well for 33% of people OK for 33% of people and not at all for 33% of people.
If you have certain genetic issues, either hereditary or somatic, it can affect how well Pluvicto Works. You can ask for a somatic test before doing Pluvicto To find out if you’ve got Genetic changes Due to the cancer.

If you have BRCA2 or ATM It seems to work better. If you have RB1, PTEN or TP53 They are Pluvicto resistant.

You might want to find out if you have any of these. You should already have gotten an hereditary, genetic test, If not, you should do that first. Then get a somatic, genetic test and see if any of your metastasis have produced these particular genetic problems, The test can be done with the sample of blood. If they are only somatic, they can come and go. In that case Pluvicto Might work in a year or two if the somatic genetic change goes away.

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Replies to "@johnravens Not sure if you’ve heard that Pluvicto works really well for 33% of people OK..."

@jeffmarc Hi,

Is there anything that works to fight Tp53? I am having a port installed on the 12th to start Taxotere. I have read that tp53 is resistant to chemotherapy. I have many bone metastases and a spot on my liver. 4 Pluvicto shots really lowered my platelets. I know the situation is dire and maybe getting near the end but I would really like to hang around with my family for a good bit longer. Thanks for your help and info