Gout and tomatoes?

Posted by carbcounter @carbcounter, May 26 11:04am

I've had various attacks of gout several times over about 25 years and long ago learned to minimize high purine foods, plus I take celery seed supplements rather than allopurinol, and this seems to help. One surprising problem food seems to be tomatoes, which have very low purines but "some people find are a trigger".
Anybody else find this a problem?
Because it had been a while, and I've sometimes bought a small fox of cherry tomatoes, and had no problems.
But I've apparently done something wrong this time and have at least a mild gout attack right now, first time even this much in several years.

So, just want to gripe publicly I guess, but if anyone has any special advice or related stories to share, I'd be happy to learn and listen!

(doesn't seem to be much traffic here about gout)

Thanks.

Interested in more discussions like this? Go to the Bones, Joints & Muscles Support Group.

Profile picture for loriesco @loriesco

@carbcounter I seriously doubt what you wrote is true. If you have gout your uric acid is high. It needs medicine to make it normal. Gout is a disease. It does not go away. During a flare it is worse. If not treated, it will cause permanent damage. If you have had a gout flare get youfr uric acid baseline done when its over. Psuedo gout and gout can happen to the same person but there is no crossover in the disease. Read the other link I posted.
There is a lot of great info here:
https://cls.health/blog/how-long-does-gout-last-without-treatment
More great info:
The Gout and Uric Acid ConnectionMisleading levels during a flare: Blood tests taken during an acute gout attack can sometimes show "normal" uric acid levels. This is because the inflammation can cause the body to temporarily excrete more uric acid, or the crystals themselves may have temporarily moved out of the bloodstream and settled into the joint.Normalizing requires treatment: Simply waiting out a flare does not resolve the root hyperuricemia (high uric acid in the blood). Without dietary changes, weight management, or uric acid-lowering medications (like allopurinol), uric acid levels will likely remain too high.The target range: To prevent future flares and allow existing crystals in your joints to dissolve, doctors generally aim to lower and maintain your blood uric acid levels to strictly below \(6.0 \text{ mg/dL}\).The Importance of Long-Term ManagementEven when you are entirely pain-free, uric acid crystals can continue to accumulate and cause permanent joint and bone damage if left unmanaged. To properly track your levels, blood tests should be conducted during "interval" periods (when you are completely flare-free) to get an accurate baseline of your uric acid control.
Here is another great article: https://creakyjoints.org/living-with-arthritis/treatment-and-care/medications/gout-stages-progression/

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@loriesco
I've been tracking my uric acid levels for years, along with triglycerides and all the other standard markers.
It runs up to the edge, but as long as there are no actual attacks I've just kept on it with general diet and the celery seed.
This "attack" has been very limited, I've been through the full attacks and they were no fun at all.

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Profile picture for carbcounter @carbcounter

@loriesco
I've been tracking my uric acid levels for years, along with triglycerides and all the other standard markers.
It runs up to the edge, but as long as there are no actual attacks I've just kept on it with general diet and the celery seed.
This "attack" has been very limited, I've been through the full attacks and they were no fun at all.

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@carbcounter my uric acid was within normal range. But now on the allopurinol, it is dead Center. That’s what you want because you may be building crystals in your joints and not realizing it. You don’t have to have flares you can just be stiff and achy. You can also be damaging your kidneys to unbeknownst to the test scores. I’ve been on a low purine diet and drink lots of fluids. keeping your uric acid in the high, although not out of range area, is not an optimal idea — Since crystals may be depositing in your joints.I haven’t had a gout flare in 20 years and I’d like to keep it that way! I come very close sometimes but I just flush a lot of fluid and/or take an extra allopurinol tablet. It’s not a dangerous medication and the side effects are not a risk. It’s a very innocuous medication.

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@loriesco
I have a checkup in a couple of months, let's see if I can do better this time with a few less carbs and a few more celery pills.
My diet is already low purine, had to pretty much give up fresh fish, sardines. Already had long given up ocean fish, except a little sushi on rare occasions, because of the mercury, so it wasn't much of a sacrifice.

I dunno, this seems like quite a list of side-effects to watch out for:
https://www.mayoclinic.org/drugs-supplements/allopurinol-oral-route/description/drg-20075476
I understand it's widely taken even so.

Thanks for your feedback, I will continue to look into things you've suggested - especially if my uric acid numbers aren't improved.

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Profile picture for carbcounter @carbcounter

@dmk
I could switch to allopurinol and my insurance would pay for it, lol, but celery seed has a very similar (or identical?) compound:
3-nbutylphthalide, or 3nB
inhibits the enzyme xanthine oxidase
xanthine oxidase inhibitor (xaoi)
... and basically no side-effects listed, nor have I had any in many years. It's not terribly expensive but it's not free!
I have not had to go on a very strict diet to mostly go without symptoms, but I suppose I'm living on the edge by doing so.
It's likely because of that, that relatively minor things like tomatoes can drag me over the edge.

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@carbcounter
An apparent correction to my 3nB information above that says 3nB by itself is nothing but a mild diuretic.

"Your understanding about the Xanthine Oxidase Inhibitor (XAOI) property is a common point of confusion. While 3nB itself is not an XAOI, whole celery seed extract does contain other compounds—specifically the flavonoids luteolin and apigenin—that have shown mild XAOI activity in laboratory settings."

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Yes, you "dunno" as you indicate. I suspect you are informed by the ideology "medicine bad" and "supplements good." Not is the case.!Celery seed has problems as well! https://www.webmd.com/vitamins/ai/ingredientmono-882/celery
Let's move on to the list you provided: Substantially Higher than the dose I take! The Allpurinol typically prescribed is 100 not 300 or 800 mcg! My father took it for years and years once he could no longer control the uric acid by his natural remedies. He died of his kidneys shutting down at 87. My aunt and grandmother stopped "moving" in their later 60s. I am just getting started at 69 and want to MOVE to offset the deterioration of a sedentary life.
PLUS, all these other "unseen" problems have now been fixed...like UTI and Interstitial Cystitis (IC). PLUS I can open the mail, weed for a few hours and exercise without the consequences of an inflammatory reaction which shuts my body down. It was all so painful!!!
So, while your body is possibly continuing to build damaging joint crystals mine is now controlled by bringing my uric acid production to PERFECTLY middle - with none of the side effects mentioned!
My doctor told me it could get worse (like your info suggests) but because I was on a low purine diet nothing adverse happened! The opposite --Its been 100% remarkable! I went to a top drawer hand/arthritis surgeon. (I am an artist). My left hand was imobilzed. There was so much arthritis he couldn't offer/recommend a surgery to fix any part of my fingers, thumb, hand, wrist. Fortunately, soon after I figured out it was gout from the Tart Cherry Capsule recommendation! Here I sit typing away and painting on a work commission with ZERO pain after 30 years of stiffness and pain! The nodules at my joints stopped increasing in size and inflammation, too. They looked like sausages two years ago!
I want my uric acid levels NORMAL. The long-term side effects of hyperuricemia (gout) are enormous and WON'T be reversed. That should concern you: https://my.clevelandclinic.org/health/diseases/17808-hyperuricemia-high-uric-acid-level
Lets talk about fish! You certainly DO NOT give up fresh fish! Just the fish which have purines! Comeon, get with the science here:
https://www.verywellhealth.com/fish-and-gout-5093098
fish, fresh caught and not farmed, white fish are a crucial part of my diet. It keeps my cholesterol/triglycerides all in check. (the fish oil supplements do zero for me) but fresh white fish drops my cholesterol to 179 -190 in short order (3 months).
I do believe in "food as medicine" however, DISEASES have special requirements. I've had a couple of "diseases" and surgeries that required medicines. Are you not going to treat Hep C with the chemo meds that cure it? A pulmonary embolism with the blood thinners, which break up the clot that dislodged after spine surgery?
The Metformin for insulin resistance so it does not go into a diabetic state?
I had a strong science, nutrition, chemistry, and health background at SDSU. I did my best during menopause 40 - 60 to go with the supplements. Now I have an old person's body and the countermeasures needed are stronger in order to live with a great quality of life, keep working and moving. Its a really delicate balancing act now.
By the way, my dad drank a squeeze of lemon in his water (all day long and that was it), and that controlled his gout until he was 80! I come from a very "natural" family that believed in natural healing methods.
Oh, my glaucoma eye pressure dropped to normal when I went on the allopurinol. So many great things!

REPLY
Profile picture for loriesco @loriesco

Yes, you "dunno" as you indicate. I suspect you are informed by the ideology "medicine bad" and "supplements good." Not is the case.!Celery seed has problems as well! https://www.webmd.com/vitamins/ai/ingredientmono-882/celery
Let's move on to the list you provided: Substantially Higher than the dose I take! The Allpurinol typically prescribed is 100 not 300 or 800 mcg! My father took it for years and years once he could no longer control the uric acid by his natural remedies. He died of his kidneys shutting down at 87. My aunt and grandmother stopped "moving" in their later 60s. I am just getting started at 69 and want to MOVE to offset the deterioration of a sedentary life.
PLUS, all these other "unseen" problems have now been fixed...like UTI and Interstitial Cystitis (IC). PLUS I can open the mail, weed for a few hours and exercise without the consequences of an inflammatory reaction which shuts my body down. It was all so painful!!!
So, while your body is possibly continuing to build damaging joint crystals mine is now controlled by bringing my uric acid production to PERFECTLY middle - with none of the side effects mentioned!
My doctor told me it could get worse (like your info suggests) but because I was on a low purine diet nothing adverse happened! The opposite --Its been 100% remarkable! I went to a top drawer hand/arthritis surgeon. (I am an artist). My left hand was imobilzed. There was so much arthritis he couldn't offer/recommend a surgery to fix any part of my fingers, thumb, hand, wrist. Fortunately, soon after I figured out it was gout from the Tart Cherry Capsule recommendation! Here I sit typing away and painting on a work commission with ZERO pain after 30 years of stiffness and pain! The nodules at my joints stopped increasing in size and inflammation, too. They looked like sausages two years ago!
I want my uric acid levels NORMAL. The long-term side effects of hyperuricemia (gout) are enormous and WON'T be reversed. That should concern you: https://my.clevelandclinic.org/health/diseases/17808-hyperuricemia-high-uric-acid-level
Lets talk about fish! You certainly DO NOT give up fresh fish! Just the fish which have purines! Comeon, get with the science here:
https://www.verywellhealth.com/fish-and-gout-5093098
fish, fresh caught and not farmed, white fish are a crucial part of my diet. It keeps my cholesterol/triglycerides all in check. (the fish oil supplements do zero for me) but fresh white fish drops my cholesterol to 179 -190 in short order (3 months).
I do believe in "food as medicine" however, DISEASES have special requirements. I've had a couple of "diseases" and surgeries that required medicines. Are you not going to treat Hep C with the chemo meds that cure it? A pulmonary embolism with the blood thinners, which break up the clot that dislodged after spine surgery?
The Metformin for insulin resistance so it does not go into a diabetic state?
I had a strong science, nutrition, chemistry, and health background at SDSU. I did my best during menopause 40 - 60 to go with the supplements. Now I have an old person's body and the countermeasures needed are stronger in order to live with a great quality of life, keep working and moving. Its a really delicate balancing act now.
By the way, my dad drank a squeeze of lemon in his water (all day long and that was it), and that controlled his gout until he was 80! I come from a very "natural" family that believed in natural healing methods.
Oh, my glaucoma eye pressure dropped to normal when I went on the allopurinol. So many great things!

Jump to this post

@loriesco
I'm actually in relatively good shape for my age, and a couple of my maladies were in no way mitigated by a series of supposedly good doctors, and that's my experience. I also saw both of my parents in their later days treated by supposedly good doctors but it didn't strike me like that at the time and with what I've learned since I'm sure it wasn't good. And this was all before COVID. SMH

So I must be doing a lot of stuff right. My cholesterol is already 170-190. Doctors would like it lower yet and the high/low density isn't perfect, but hey.

I'm glad the allopurinol is out there, and it's probably the drug I'm not taking that I'm closest to taking. There are one or two others. I never turn anything down that I need, or that is a slam-bang cure, but there are surprisingly few of those around. Hep-C is one that there are cures for now, which is pretty amazing, but fortunately I haven't needed it.

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Profile picture for carbcounter @carbcounter

@loriesco
I'm actually in relatively good shape for my age, and a couple of my maladies were in no way mitigated by a series of supposedly good doctors, and that's my experience. I also saw both of my parents in their later days treated by supposedly good doctors but it didn't strike me like that at the time and with what I've learned since I'm sure it wasn't good. And this was all before COVID. SMH

So I must be doing a lot of stuff right. My cholesterol is already 170-190. Doctors would like it lower yet and the high/low density isn't perfect, but hey.

I'm glad the allopurinol is out there, and it's probably the drug I'm not taking that I'm closest to taking. There are one or two others. I never turn anything down that I need, or that is a slam-bang cure, but there are surprisingly few of those around. Hep-C is one that there are cures for now, which is pretty amazing, but fortunately I haven't needed it.

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@carbcounter you might just have good genes! I seem to have inherited medical problems that are due to genetics. i’ve been able to benefit from a lot of great information by having done my DNA and learning about my genetic mutations. I am grateful for the medicines that are out there which have helped me along the way. Good luck on continued good health!

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Yes, have to be fortunate to have good genes. Never had mine done, no doctor has yet suggested it though that's the way a lot of medicine is going these days. But looking around at family overall not a lot of exotic problems, just like most people, respond to healthy habits and modern medicine. One set of grandparents did pretty well as they got old, the other set not so much, but it went with their habits, too.

Dad had a little gout, took allopurinol for a couple of months at a time once or twice, that was about it. Maybe one actual gout attack in middle age, then just watching the numbers afaik.

Good luck to us all!

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