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← Return to AML, age 78, taking Decetabine/ Venetoclax, no transplant
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AML, age 78, taking Decetabine/ Venetoclax, no transplant
Blood Cancers & Disorders | Last Active: Jun 1 9:47am | Replies (80)Comment receiving replies
@loribmt
I echo the comments of others in thanking you for posting and your guidance on topics related to AML.
I am in deep remission after induction therapy (no BMT) treatment has been Venetaclax and Dacogen for 2 years. I am being transitioned to INQOVI starting June 23rd.
I am wondering if you know how others taking this chemo pill have tolerated it. I have a video call scheduled with the pharmacist to cover the side effects. With my care team I will still get blood draws every other week, MRD blood draw in April showed no evidence of my FLT3 or NPM1 mutations and MRD draw will be every 4-5 months (next one will be August) and yearly BMB in December. Last Dec BMB discovered the SF3B1 mutation. My Hem/Onc said Inqovi has shown promise in controlling the SF3B1 mutation. Any knowledge you or members reading this post can share will be greatly appreciated. Thank you again!
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Good morning @sonieaml
Earlier this month (May 2026) the FDA approved INQOVI in combination with Venetoclax, for the first all-oral combination treatment for patients (75 yrs of age) or, patients with AML who aren’t eligible for intensive chemo. In the trial, treatment with INQOVI (which is decitabine/cedazuridine) plus Venetoclax yielded a complete remission (CR) rate of 41.6% and a CR rate of 52.5% in patients ineligible for intensive induction chemotherapy. That’s impressive!
There have been some really promising breakthroughs over the past few years for us folks over 70!
I did a quick search to see mentions of other members taking INQOVI for MDS or AML. Here’s a link to the search:
https://connect.mayoclinic.org/search/
It’s fantastic news that you’re showing no evidence of the FLT3 or NPM1 mutations!! FLT3 can be a bad actor! So I’m thrilled for you! The V & D regime has worked! Wishing you continued success as you transaction to the INQOVI. It looks to be another promising drug!
Thank you again for sharing your journey all along with us. It brings hope and inspiration to AML Warriors! ☺️
Have you been able to stop taking the venetoclax and dacogen for now?