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Anyone tried Votrient (pazopanib)?
Sarcoma | Last Active: Jun 9 9:07am | Replies (10)Comment receiving replies
I am so glad I came across this. I have Leiomyosarcoma and feel so alone as it’s hard to find others that have it. I was recently put on pazopanib as all the other heavy duty chemos were either not working or I hit the lifetime limit. Basically for me the hope is this will work long enough for another treatment or trial to show up on the scene. By body handles chemo exceptionally well but the tumors are not responding. On this new one the biggest issue is blood pressure is skyrocketing and they are having trouble keeping it normal and also I can not be on omeprazole alas it interacts and so my gerd is quite out of control. Otherwise, so far, very few symptoms.
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@thia1125, how long have you been on pazopanib now? How are you doing?
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@thia1125 Hello.....my Wife has leiomyosarcoma and has been treated with Votrient(pazopanib) for about 15 months. Her side effects are mainly GI issues and hair thinning, plus an altered sense of taste that varies. There has been some variability in her liver function numbers, but that is stable currently. We're pleased that this medication has brought her "stable" readings on her scans. She found success by slowly increasing her dosage from 200mg to 600mg at present. Not many find success at 800mg because of increased side effects. As always, each patient is unique and will have different experiences with medications. Wishing you the best in your treatment journey!!