Not all probiotics are equal. I've been taking two probiotics and one pre-biotic for five years. I have radiation proctitis and pc. My proctitis has been treated with about 16 months of enemas. I have been mostly symptom free since having 30 hyperbaric oxygen treatments (aka "dives"). BTW I was able to self-administer enemas with a syringe with a rounded catheter tip. I can send you details if desired.