Linzess did NOT work for me.. and actually made me sort of sick..I'm on Trulance..andVSL-3 probiotics..miralaxing occasionally when I have a reaction to food or medication..then I might MiraLAX 3 times a day.. don't want to go to ER anymore for this!! Also prune juice helps and pear juice (but pear juice can really hurt your stomach if you drink it on an empty stomach..ouch!!) I think it has alot more sorbitol than prune juice..tastes better for sure!! And yes small meals several times a day.. and lots of water!! Prayers for you!!