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PET Scan or not yet?

Prostate Cancer | Last Active: 8 hours ago | Replies (27)

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Profile picture for surftohealth88 @surftohealth88

@kujhawk1978

I agree 100% with 0.08 not being of concern on it's own, it is just that this patient has one lymph node positive - I mean, one was found, who knows if there are more : ((( .
Also, I found some studies that discovered that once patient reaches 0.03 post op there BCR is going to happen sooner or later. I am so upset that I did not save the link but this is Google summery :

"The Clinical Meaning of 0.03 ng/mLPredictive Value: Research indicates that a uPSA level of \(0.03 \text{ ng/mL}\) or higher reliably identifies patients who will eventually experience BCR.
Lead-Time Advantage: Traditional BCR is typically defined as a PSA level rising to \(> 0.2 \text{ ng/mL}\). Using the \(0.03 \text{ ng/mL}\) cutoff provides an average "lead time" advantage of roughly 18 months, alerting your care team to rising levels well before traditional thresholds are met.
Independent Marker: Studies (such as the landmark UCLA study) show that achieving an undetectable uPSA (often \(< 0.01 \text{ ng/mL}\)) offers the highest chance of long-term remission, whereas crossing \(0.03 \text{ ng/mL}\) serves as an independent predictor of recurrence regardless of other risk factors."

Wishing you fantastic vacation 😎👍
Enjoy : )))) !!!!

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Replies to "@kujhawk1978 I agree 100% with 0.08 not being of concern on it's own, it is just..."

@surftohealth88

Interesting...

So, a PSA of .03 is predictive of BCR around 18 months later.

In my case yes, it can.

The question remains, what is one's trigger for initiating treatment?

For me and my medical team, our criteria remains:

Three or more PSA tests spaced three months apart

AND/OR

PSA between .5-1.0

As I've said, those criteria ensure care acting in a trend, not a blip, and gives us a reasonable chance of imaging finding it thus informing a treatment decision. We do not feel it entails any risk in my PCa becoming unmanageable with definitive treatment.

It's hard making a treatment decision, guidelines, clinical trials, clinical data, choices - when, with what, for how long, de-intensification...

Kevin

My PSA is .03 now and has been for just about two years. My oncologist says my PSA is stable...

Will I see yet another recurrence, likely, given my clinical history and data, I am not cured.

So, my statement may have been too generalized, but I think my point holds true, exercise discretion about when to initiate treatment.

I've been off treatment for two years with a stable PSA of .03, hot flashes, fatigue, muscle and joint stiffness gone, weight back down, genitalia back to "normal...