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← Return to PET Scan or not yet?
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Prostate Cancer | Last Active: 8 hours ago | Replies (27)
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@surftohealth88 It is, I was thinking the concept was applicable, not acting at .08...
This is not an exact fit either - https://www.urotoday.com/recent-abstracts/urologic-oncology/prostate-cancer/168250-natural-history-of-untreated-prostate-cancer-a-comprehensive-review-of-long-term-progression-patterns-and-survival-outcomes-beyond-the-abstract.html
It goes to my point though about USPSA, just because we can measure to 2-3 decimal places, does it mean we have to do something? Certainly we understand at PSA .3 or less, statistically our chances of a cure are better., ,08 though, ok...nice to know, let's schedule our next labs and consult for...?
Meanwhile, the wife and I are going on a vacation...!
Replies to "@surftohealth88 It is, I was thinking the concept was applicable, not acting at .08... This is..."
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@kujhawk1978
I agree 100% with 0.08 not being of concern on it's own, it is just that this patient has one lymph node positive - I mean, one was found, who knows if there are more : ((( .
Also, I found some studies that discovered that once patient reaches 0.03 post op there BCR is going to happen sooner or later. I am so upset that I did not save the link but this is Google summery :
"The Clinical Meaning of 0.03 ng/mLPredictive Value: Research indicates that a uPSA level of \(0.03 \text{ ng/mL}\) or higher reliably identifies patients who will eventually experience BCR.
Lead-Time Advantage: Traditional BCR is typically defined as a PSA level rising to \(> 0.2 \text{ ng/mL}\). Using the \(0.03 \text{ ng/mL}\) cutoff provides an average "lead time" advantage of roughly 18 months, alerting your care team to rising levels well before traditional thresholds are met.
Independent Marker: Studies (such as the landmark UCLA study) show that achieving an undetectable uPSA (often \(< 0.01 \text{ ng/mL}\)) offers the highest chance of long-term remission, whereas crossing \(0.03 \text{ ng/mL}\) serves as an independent predictor of recurrence regardless of other risk factors."
Wishing you fantastic vacation 😎👍
Enjoy : )))) !!!!