Hello @rramsey -- Welcome to Connect. You asked a really good question but I'm not sure there is any authority that can provide an all encompassing answer. I think there are variables and you would need to discuss the benefits and risks for your specific health issues.

I have idiopathic small fiber PN and I wear compression socks. I also have lymphedema which is why I need to wear the compression socks. My right leg and ankle have swelling that increases throughout the day. My Mayo cardiology doctor prescribed the compression socks to help with the swelling and I'm also supposed to elevate the leg frequently throughout the day which doesn't always happen.

Have you discussed wearing compression socks with your neurologist or doctor and asked if it is safe?