@heavyphil Yes. ROs are like anybody else, doing what they know and reluctant to change. Second opinions are important. I found that out when my RO, otherwise ready to go with a round of radiation based on what he saw from a PET scan, informed me that the machine he wanted to put me on was down, and maybe I should look elsewhere for radiation. I did, and I'm now going through a far more careful process with the team at Johns Hopkins, who saw that radiation to one area carried significant risk of organ damage. That could have been me. The drugs we're all on put PC to sleep, so we have the time to be cautious about treatment. Get the second opinion.