Replies to All ADT and T loss contributes to muscle atrophy and bone loss.. And yes Prolia and...

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Prostate Cancer | Last Active: May 18 12:58pm | Replies (9)

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All ADT and T loss contributes to muscle atrophy and bone loss.. And yes Prolia and other similar drugs can actually increase fracture risk (study osteoblasts and osteocasts appearing to be more dense but fragility increases....) plus I used to take Calcium supplements and that contributed to calcified aortic valve; eventually had valve replaced (TAVR). Calcium is not smart and doesn't know you want it go to to the bones not heart.

The other thing on my mind is whether if you're 80 or older one ought to discontinue Orgovyx or anything; if you have localized PC; because by the time it breaks out you're near 90. Plus low T accelerates aging, right?

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Replies to "All ADT and T loss contributes to muscle atrophy and bone loss.. And yes Prolia and..."

Jeff Marchi | @jeffmarc | May 18 12:21pm

@seer
I know in my case low T has not accelerated aging. People are pretty surprised when I tell them I’m 78, they think I’m at least 10 years younger. Not only do I look younger, but I am very active, I walk a mile on the track twice a day every day at good speed and I go to the gym three days a week and exercise with weights the whole time. The track I go to is near a middle school and those kids run/walk on that track Every day. I’m constantly passing them up if they’re walking.

I get blood tests every month and the test for kidneys, liver, thyroid come back normal. I have relatively low blood pressure.

Results really do vary with low T.

I’ve been on ADT for over eight years.

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