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Bone turnover markers (CTX and P1NP): do you have a baseline?
Osteoporosis & Bone Health | Last Active: 32 minutes ago | Replies (293)Comment receiving replies
@singingbones i used Forteo then transitioned to HRT with no other osteoporosis meds, so estrogen serves as an antiresorptive during my maintenance phase.
Since CTX (resorption) tends to have a small rebound toward or above baseline within 1–3 months of stopping Evenity, and the fact that it takes a few months for estrogen to reach max effect, having 3-4mos of HRT already in place like you have is a huge plus in my view.
Have you checked your CTX labs? I think it’s a great way to verify HRT's effect. My doctors don't focus on serum estradiol levels, but they check my CTX periodically and order annual DXA scans.
Hope this info helps somewhat. Best of luck and please keep us posted.
Replies to "@singingbones i used Forteo then transitioned to HRT with no other osteoporosis meds, so estrogen serves..."
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@mayblin - My ortho dr does not plan to run any BTM as far as I know b/c my DXA is due at the end of the Evenity treatment & she says that makes it unnecessary to run the markers. She did run the P1NP & BSAP (bone-specific Alkaline Phosphatase) before starting me on Evenity, however.
Assuming she doesn't order the BTMs, I plan to ask my PCP if she will run them so I have a baseline of my own even if it's already impacted by residual Evenity & early HRT. If she won't order, then I'll self-pay for those two as well as CTX.
After all my research, I see no reason why HRT won't hold the post-drug gains. My BTMs & perhaps a REMS scan can both serve to check in on my progress or regression.
Thanks for sharing your story/strategy & yes, I'll keep you posted.