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@jeffmarc Curious, Jeff…didn’t Dr Weisserug prove to you that notion to be false in an email he sent you?That being on ADT early prevents castrate resistant clones from developing? And that long term ADT does not automatically cause castrate resistance?
He has been on Estradiol patch for like 16 yrs and is doing well so far…thoughts? Best,
Phil

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Replies to "@jeffmarc Curious, Jeff…didn’t Dr Weisserug prove to you that notion to be false in an email..."

@heavyphil
He said essentially that the cancer cells will accumulate and get hit by cosmic rays and then convert to resistance.

It makes me think that when you are on ADT some cells still accumulate but if you are on estradiol, you don’t have that problem. I don’t know if that is true, I do know the few people that I know of that are on estradiol do not have a problem yet. And some people that were on ADT for many years alone, didn’t have that problem.

I do know that I was on only ADT for 2 1/2 years and became castrate resistant. Something happened to those cells. Predictions of how soon somebody will become castrate resistant after being on ADT alone say, it’s a median of two years.