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@kapow

Your vulnerability to blood clots depends on SO MANY factors.

Speaking very generally: Relative to those with the JAK2 driver, MPLs like you and me, as well as CALs and triple-negatives, are less prone to clots.

But, compared to everyone who doesn't have it, anyone with ET has an increased risk of clots.

Remember! Every time you take the meds prescribed by your doctor

-- you are saying NO THANK YOU to blood clots.

Some helpful background from Blood Cancer UK:

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When you have ET, your body starts making too many blood cells called platelets.

Platelets are blood cells that help your blood to clot. They stick together to stop you bleeding if you have a cut or a bruise.

Like most blood cells, platelets are made inside your bone marrow – the spongy material inside some of your bones. Large cells in your bone marrow called megakaryocytes produce platelets that are released into your bloodstream, ready to stop the bleeding if you are injured.

In ET, the megakaryocytes start to make too many platelets. That means your blood may clot too easily. This can cause a heart attack or stroke and a range of other symptoms.

Treatments for ET aim to manage these symptoms and lower your risk of developing blood clots.

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Replies to "@kapow Your vulnerability to blood clots depends on SO MANY factors. Speaking very generally: Relative to..."

@janemc Thank you for this explanation. I guess I am proof that it doesn’t really matter which driver mutation you have, blood clots are possible and our enemy. Keeping the platelet count down by following our doctor’s instructions on medication is very important. And has been stated several times …..everyone is different.