@chilla I am in your camp. I am now pinching myself to see if this isn't a dream. I have battled bronchiectasis for ten years. I did everything in my power to change the course of my battle with constant coughing, 150cc of sputum per day, and basically curtailing my social life out of fear of acquiring a new infection.

I started on Brinsupri November 1, 2025. I have not had an infection since then. First month felt a bit of flulike symptoms but other than that no side effects. My mucous production is now around 15 to 30cc. Two years ago I would cough and spit every block on my five mile walk. Now I can walk cough free. I can sleep without waking up to coughing jags lasting an hour.

I am now contemplating traveling again. Life changing.

I actually wish there was a study to see why some of us are responding so well and others are not experiencing any benefit or side effects to the point they want to stop taking the medication. I will say I have never tested positive for pseudomonas or the NTM bacterias. I have had every other one though so it has been a challenge.

I am due for a repeat CT Scan soon and that will be objective evidence IMO.

I am happy for you @chilla and as grateful. Let us hope for others struggling to see such results too.