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Hi @rimmy2 Blood cancers and conditions can be complicated and not always easy to pinpoint with the subtle characteristics within a group. It can take some sleuthing with testing such as the flow cytometry your husband just had. To answer your question, yes! Flow cytometry is often part of routine testing to confirm CLL or any blood cancer really. It can help spot certain markers that are unique to a specific disease.

So try not to read too much into this. I know you’re on pins and needles while waiting for a confirmation. This is where I’m going to encourage you to not go trolling for information online because anything you’re looking at right now is mere speculation and really feeds into that anxiety pot! Right? ☺️

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Replies to "Hi @rimmy2 Blood cancers and conditions can be complicated and not always easy to pinpoint with..."

@loribmt
Good advice. It’s hard to wait. Thank you.

@loribmt
Have you ever heard of having cll/small lymphocytic lymphoma at the same time? Or 2 distinct cell populations? One 28%- cll/sll the other 5% which is unclear.

The doctor said there needs to be more tests. My husband’s flow cytometry identified the flowing-

2 distinct cell populations. The report ended with-

Taken together, these results demonstrate the presence of 2 clonal B cell populations. The immunophenotype of the
predominant population (28% of the total sample) is characteristic of chronic lymphocytic leukemia/small lymphocytic
lymphoma. The significance and relationship of the second smaller population (5%) is unclear (not typical CLL
immunophenotype and different light chain expression). This population may represent non-CLL type MBL or low
level involvement by an unrelated B cell lymphoproliferative disorder. Correlation with clinical and other lab data is
suggested (evaluate for splenomegaly and lymphadenopathy to exclude involvement of other sites.)

I’m not asking for a diagnosis, just wanting to know if you or anyone on here has had 2 distinct cell populations. One of which isn’t evident of what it exactly is.

Thanks in advance.