I don't know what med your taking but studies show that AIs and cdk4/6 inhibitors can have dose reductions without affecting efficacy. AIs like letrozole can be changed to every other day. I take both letrozole and Kisqali. No problems with letrozole, but the cdk4/6 inhibitor Kisqali gave me neutropenia severe enough to reduce dose from 600mg to 400mg and finally 200mg where I still have reduced neutrophils but manageable. I wouldn't dose adjust any med without discussing with your onc but it is doable and certainly better than doing without.