2 Decipher Tests, Which one should be used for treatment??

Posted by jnlracer18 @jnlracer18, May 11 10:19pm

Husband diagnosed in Nov 2021, had a Decipher test done on the biopsy BEFORE surgery. Decipher score was .68.
In 2023, PSA started rising, fast forward while monitoring the PSA, in 2025 did another Decipher Score Test. This one was .49. They are treating him based on the first one from the biopsy. I would think that with a Decipher test score of .49, being done with the whole prostate, that one should be more reliable, no? Anybody have an answer? Please help!! Thanks in advance. I will be asking the doctor next month when we go for a follow up with the radiation oncologist.

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On our last consult with RO we were offered to have Decipher done again. Now, don't ask me why or how is it done, I did not ask since I had more pressing questions on my mind. It was offered as "by the way" and we said "OK, ...sure..." - I have no idea why it can be helpful or how it can be different in our case of original Decipher score of 1 ???! ANYHOW, we get tests that have purely empirical value and have to fight for really relevant tests lol , oh how fun it is to be us 😆👍 ! Never a day of boredom !!! 😝

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@jeffmarc Gleason score was 3+4, PSA at dianosis was 14.4. Yes there was some sort of spread, think it was ECE. found in one node at time of prostate removal. 15 month doubling time, which is slow. On Orgyvox now and did 25 rounds of radiation. Finished in Feb.

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@jnlracer18
You say that your PSA didn’t go up fast, Did you have radiation because Of the ECE, They wanted to get ahead of it and give you adjuvant radiation?

I sure hope you have no further problems. It definitely seem they really attacked it in the hopes of eliminating it.

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